Blood volume in monoclonal gammopathy

Blood volume in monoclonal gammopathy.

The plasma volume, red cell volume, or both were measured in 170 normal, anemic, or polycythemic subjects. For anemic subjects without a serum protein abnormality or splenomegaly, the relationship between hematocrit and red cell volume was linear and predictable. In patients with a serum monoclonal globulin on electrophoresis, the plasma voluem was significantly increased for the hematocrit in ...

Herpes Encephalitis in Monoclonal Gammopathy

Ninety percent of adult cases of encephalitis are caused by herpes simplex virus (HSV) type 1, and HSV type 2 encephalitis is clinically indistinguishable from HSV-1 encephalitis. There have been reports of HSV encephalitis in patients who have multiple myeloma and plasmacytoma,1-3 but this is the first case report describing HSV encephalitis in a patient with monoclonal gammopathy of unknown s...

HIV, EBV, and monoclonal gammopathy.

In this issue of Blood, Ouedraogo et al have investigated the role of HIV and Epstein-Barr virus (EBV) replication in the persistence of monoclonal gammopathy.1 It has been known for some time that patients with HIV infection have an increased incidence of monoclonal gammopathy and plasma cell dyscrasias.2,3 The exact mechanism of monoclonal gammopathy in patients with HIV infection is unknown,...

Monoclonal gammopathy and rheumatic diseases.

It is common to find monoclonal gammopathy in the investigation workout for an unrelated disorder. There are studies relating rheumatic diseases and therapies which show an increased risk of monoclonal gammopathy. The specific mechanisms are not well understood but chronic antigen stimulation assumes an important role. Specific rheumatic diseases have consistently been associated with lymphopro...

Monoclonal gammopathy of undetermined significance.